Amelotin: an enamel matrix protein that experienced distinct evolutionary histories in amphibians, sauropsids and mammals
نویسندگان
چکیده
منابع مشابه
Global Patterns of Evolutionary Distinct and Globally Endangered Amphibians and Mammals
BACKGROUND Conservation of phylogenetic diversity allows maximising evolutionary information preserved within fauna and flora. The "EDGE of Existence" programme is the first institutional conservation initiative that prioritises species based on phylogenetic information. Species are ranked in two ways: one according to their evolutionary distinctiveness (ED) and second, by including IUCN extinc...
متن کاملTargeted Overexpression of Amelotin Disrupts the Microstructure of Dental Enamel
We have previously identified amelotin (AMTN) as a novel protein expressed predominantly during the late stages of dental enamel formation, but its role during amelogenesis remains to be determined. In this study we generated transgenic mice that produce AMTN under the amelogenin (Amel) gene promoter to study the effect of AMTN overexpression on enamel formation in vivo. The specific overexpres...
متن کاملAmelotin Gene Structure and Expression during Enamel Formation in the Opossum Monodelphis domestica
Amelotin (AMTN) is an ameloblast-secreted protein that belongs to the secretory calcium-binding phosphoprotein family, which also includes the enamel matrix proteins amelogenin, ameloblastin and enamelin. Although AMTN is supposed to play an important role in enamel formation, data were long limited to the rodents, in which it is expressed during the maturation stage. Recent comparative studies...
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Methods We digitized lizard distribution data to generate gridded maps of species richness and b-diversity. Using similar maps for amphibians, mammals and birds, we explored the relationship between species richness and temperature, actual evapotranspiration, elevation and local elevation range. We used spatial eigenvector filtering and geographically weighted regression to explore geographical...
متن کاملThe ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories.
The RNase A superfamily has been important in biochemical, structural, and evolutionary studies and is believed to be the sole vertebrate-specific enzyme family. To understand the origin and diversification of the superfamily, we here determine its entire repertoire in the sequenced genomes of human, mouse, rat, and chicken. We report a previously unnoticed gene cluster in mouse chromosome 10 a...
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ژورنال
عنوان ژورنال: BMC Evolutionary Biology
سال: 2015
ISSN: 1471-2148
DOI: 10.1186/s12862-015-0329-x